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James Marcus is a character in the Resident Evil series. He appears as the main antagonist in Resident Evil 0. Marcus was one of the original founders of the Umbrella Corporation, alongside Ozwell E. Spencer and Edward Ashford. Marcus was assinated by Albert Wesker and William Birkin, under the orders of Spencer. Marcus was resurected by his experimental leeches, and eventually put to rest permanantly by Billy Coen.

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